Medicine

Comparative study of immune biomarkers and oxidative stress in patients with COVID-19, dengue, and malarial infection

Authors

  • Saima Zaheer

    The University of Lahore, Sargodha campus
    Author

  • Nida Aslam

    The University of Lahore, Sargodha campus
    Author

  • Hufsa Ahmad

    Department of Chemistry, The University of Lahore, Sargodha campus, 40100 Sargodha Pakistan
    Author

DOI:

https://doi.org/10.71107/kx29gt92

Keywords:

Malaria, Dengue, COVID-19, Oxidative stress, Biomarkers

Abstract

Dengue, a vector-borne virus-related contamination transferred by the Aedes mosquito. Malaria remains a main transferrable infection that affects billions of people, once diseased with Plasmodium organisms. The COVID-19 (coronavirus disease 2019) that took over the world in December 2019 has everlasting distressing effects on people's lives worldwide. Coronavirus infection is extremely contagious and pathogenic biological contamination produced by the severe respirational disorder coronavirus 2 (SARS-CoV-2), which affected the global epidemic. A significant decrease (P <0.05) of GSH was observed in different groups of patients with dengue and malaria, while a significant increase in COVID-19. A Significant decrease in catalase in dengue, malaria, and COVID-19 was observed. Significant results in decreasing trend of vitamin C in dengue, malaria, and COVID-19 observed. In the peripheral film, ESR in dengue patients increased by 11.62±3.85 in malarial patients by 53.52±26.14 and in COVID-19 patients it is observed at 6.70±2.91. CRP increasing trends were observed in all groups. To perform a comparative chemical analysis of patients with COVID-19, dengue, and malaria by evaluating key biochemical markers, oxidative stress parameters, and immune profiles, to identify distinctive patterns, overlapping features, and potential diagnostic or prognostic indicators associated with each infection.

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Author Biographies

  • Saima Zaheer, The University of Lahore, Sargodha campus

    Ms. Saima is the lecturer at UOL

  • Nida Aslam, The University of Lahore, Sargodha campus

    Ms. Nida is the MPhil research student at UOL

  • Hufsa Ahmad, Department of Chemistry, The University of Lahore, Sargodha campus, 40100 Sargodha Pakistan

    Department of Chemistry, The University of Lahore, Sargodha campus, 40100 Sargodha Pakistan

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Published

2025-04-17

Issue

Vol. 1 No. 1 (2025): Conclusions in Medicine

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Articles

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Copyright (c) 2025 Saima Zaheer, Nida Aslam, Hufsa Aslam (Author)

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This work is licensed under a Creative Commons Attribution 4.0 International License.

How to Cite

Comparative study of immune biomarkers and oxidative stress in patients with COVID-19, dengue, and malarial infection. (2025). Conclusions in Medicine, 1(1), 25-32. https://doi.org/10.71107/kx29gt92